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KMID : 0984720040360020092
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Infection and Chemotherapy
2004 Volume.36 No. 2 p.92 ~ p.96
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The Comparison of Microscopic Urine Sediment, Nitrite, and Leukocyte Esterase Tests for Bacteriuria
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Shin Bo-Moon
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Abstract
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Background : Although bacteriologic culture remains the gold standard for detecting bactriuria, leukocyte esterase. nitrite and urine microscopy are also widely used. However. it is not uncommon to be presented with a discrepancy between these tests.
Methods : We performed leukocyte esterase and nitrite tests by urine reagent ship testing (Combur 10 "Pest, Ro he. Germany), microscopic urinalysis, and by bacteriologic urine culture on 2W persons.
Results : The number of pathogens and non-pathogens were 51 (17.6%) and 87 (30.0%) respectively. The number of cases in which no microorganism was isolated (NNII group) was 152 (52.4%). The concordance rate between leukocyte esterase and microscopic leukocytes (leukocyturia) was 70.7%. The sensitivities and specificities of leukocyte esterase, microscopic leukocyte and microscopic bacteria were 72.5%/61.8%, 76.5%/44.1 and 80.4%/92.1% respectively, and their positive predictive values and negative predictive values were 24% (62.3%)/69.1% (89.7%), 21.3% (53.6(/1o)/62.6% (88.8%) and 51.9% (84.8%)/66.4% (95.3%), respectively. Although the nitrite test showed higher positive rates in the pathogen groups (37.2%) than in the non-pathogen group (2.2%) and NM group (1.3%), this was only marginally significant.
Conclusion : The microscopic estimation of bacteria is more a predictable marker of bacteriuria, rather than leukocyte esterase, nitrite, and microscopic leukocytes, in urine.
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KEYWORD
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Leukocyte esterase, Leukocyturia, Nitrite, Bacteriuria
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